100000 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 100010 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 100020 - Disclosure - Commitments and Contingencies - Schedule of Future Minimum Payments Under Non-cancellable Purchase Obligations (Details) 2 link:presentationLink link:calculationLink link:definitionLink 100030 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 100040 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:presentationLink link:calculationLink link:definitionLink 100050 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (PARENTHETICAL) link:presentationLink link:calculationLink link:definitionLink 100060 - Statement - CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDER'S DEFICIT link:presentationLink link:calculationLink link:definitionLink 100070 - Statement - CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDER'S DEFICIT(Parenthetical) link:presentationLink link:calculationLink link:definitionLink 100080 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 100090 - Disclosure - Nature of the Business and Basis of Presentation link:presentationLink link:calculationLink link:definitionLink 100100 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 100110 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 100120 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 100130 - Disclosure - Prepaid Expenses and Other Current Assets link:presentationLink link:calculationLink link:definitionLink 100140 - Disclosure - Accrued Expenses link:presentationLink link:calculationLink link:definitionLink 100150 - Disclosure - License and Collaboration Agreements link:presentationLink link:calculationLink link:definitionLink 100160 - Disclosure - Population Health Partners, L.P link:presentationLink link:calculationLink link:definitionLink 100170 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 100180 - Disclosure - Convertible Preferred Stock link:presentationLink link:calculationLink link:definitionLink 100190 - Disclosure - Common Stock link:presentationLink link:calculationLink link:definitionLink 100200 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 100210 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 100220 - Disclosure - Defined Contribution Plan link:presentationLink link:calculationLink link:definitionLink 100230 - Disclosure - Net Loss per Share link:presentationLink link:calculationLink link:definitionLink 100240 - Disclosure - 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Disclosure - Accrued Expenses (Tables) link:presentationLink link:calculationLink link:definitionLink 100340 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 100350 - Disclosure - Convertible Preferred Stock (Tables) link:presentationLink link:calculationLink link:definitionLink 100360 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 100370 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 100380 - Disclosure - Net Loss per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 100390 - Disclosure - Selected Quarterly Financial Data (unaudited) (Tables) link:presentationLink link:calculationLink link:definitionLink 100400 - Disclosure - Nature of the Business and Basis of Presentation - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100410 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100420 - Disclosure - Summary of Significant Accounting Policies - Summary of Estimated Useful Life of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 100430 - Disclosure - Summary of Significant Accounting Policies - Summary of the impact of the adoption (Details) link:presentationLink link:calculationLink link:definitionLink 100440 - Disclosure - Marketable Securities - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100450 - Disclosure - Marketable Securities - Summary of Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 100460 - Disclosure - Fair Value Measurments - Asset and Liabilities Measured at Fair Value on Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 100470 - Disclosure - Fair Value Measurements (Additional Information) (Details) link:presentationLink link:calculationLink link:definitionLink 100480 - Disclosure - Prepaid Expenses and Other Current Assets - Summary of Prepaid Expenses and Other Current Assets (Details) link:presentationLink link:calculationLink link:definitionLink 100490 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 100500 - Disclosure - License and Collaboration Agreements - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100510 - Disclosure - Population Health Partners, L.P (Additional Information) (Details) link:presentationLink link:calculationLink link:definitionLink 100520 - Disclosure - Commitments and Contingencies - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100530 - Disclosure - Commitments and Contingencies - Schedule of Future Minimum Payments Under Non-cancellable Purchase Obligations (Details) link:presentationLink link:calculationLink link:definitionLink 100540 - Disclosure - Commitments and Contingencies - Schedule of operating lease expense (Details) link:presentationLink link:calculationLink link:definitionLink 100550 - Disclosure - Convertible Preferred Stock - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100560 - Disclosure - Convertible Preferred Stock - Schedule of Preferred Stock (Details) link:presentationLink link:calculationLink link:definitionLink 100570 - Disclosure - Common Stock - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100580 - Disclosure - Stock-Based Compensation - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100590 - Disclosure - Stock-Based Compensation - Schedule of Weighted Average Fair Values and Valuation Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 100600 - Disclosure - Stock-Based Compensation - Summary of Stock Options Activity (Details) link:presentationLink link:calculationLink link:definitionLink 100610 - Disclosure - Stock-Based Compensation - Schedule of Unvested Common Stock From Option Early Exercises (Details) link:presentationLink link:calculationLink link:definitionLink 100620 - Disclosure - Stock-Based Compensation - Summary of Share Based Compensation Expense Recognized (Details) link:presentationLink link:calculationLink link:definitionLink 100630 - Disclosure - Stock-Based Compensation - PHP Warrants outstanding for the year (Details) link:presentationLink link:calculationLink link:definitionLink 100640 - Disclosure - Stock-Based Compensation - Schedule of Weighted Average Fair Value Assumptions in PHP Warrants (Details) link:presentationLink link:calculationLink link:definitionLink 100650 - Disclosure - Income Taxes - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100660 - Disclosure - Income Taxes - Schedule of Effective Income Tax Rate (Details) link:presentationLink link:calculationLink link:definitionLink 100670 - Disclosure - Income Taxes - Summary of Net Deferred Tax Assets (Details) link:presentationLink link:calculationLink link:definitionLink 100680 - Disclosure - Defined Contribution Plan - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100690 - Disclosure - Net Loss per Share - Schedule of Earning Per Share, Basic and Diluted (Details) link:presentationLink link:calculationLink link:definitionLink 100700 - Disclosure - Net Loss per Share - Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 100710 - Disclosure - Related Party Transactions - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 100720 - Disclosure - Selected Quarterly Financial Data (unaudited) - Schedule of Quarterly Financial Information (Details) link:presentationLink link:calculationLink link:definitionLink 100730 - Disclosure - Selected Quarterly Financial Data (unaudited) - Schedule of Quarterly Financial Information (Parenthetical) (Details) link:presentationLink link:calculationLink link:definitionLink